Morales, who played for the Los Angeles Angels' Triple-A affiliate in Salt Lake City from 2006-2008, ripped a fastball over the left center fence in the top of the fourth inning and Smoak went deep in the fifth to help the Mariners finish with the best spring training record in team history at 22-11.
Troy Tulowitzki and Todd Helton both hit solo home runs to chase Brandon Maurer, who is slated to be Seattle's fourth starter. The Rockies had the bases loaded in the eighth after Jordan Robera's single scored David Kandilas and trimmed the lead to a run.
Raul Ibanez caught Jonathan Herrera's line drive on a full sprint toward the infield.
Rockies second baseman Josh Rutledge left the game after colliding with right fielder Michael Cuddyer in pursuit of Jesus Montero's blooper down the right field line. After lying on the ground for a couple minutes, Rutledge walked slowly to the dugout under his own power and is expected to fill his No. 2 batting spot in the opening day lineup Monday.
Stephen Pryor won in relief and Bryan Sweeney earned his first save of the spring. Rex Brothers lost.